The CLN2 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CLN2, LPIC, and TPP1. This antibody recognizes Human antigen. The CLN2 antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]